KPV
Topical or oral · coming soon
KPV is the last three amino acids of alpha-MSH, a hormone your body makes that helps regulate inflammation. It keeps the hormone’s anti-inflammatory action without its tanning effect, and you take it by mouth or on your skin. No needles. Now it’s coming to SuccessRx: prescribed by a licensed provider and made by a state-licensed U.S. pharmacy.
Ordering opens soon
See what I can start todayKPV isn’t available to order yet. Prices post here the day it opens.
Prescribed by licensed U.S. providers. Prepared by state-licensed U.S. pharmacies.
What’s in your plan
- An online visit and review by a licensed U.S. provider
- KPV prepared for you by a state-licensed U.S. pharmacy
- Supplies and step-by-step instructions for your form
- Messaging with your care team in your patient portal
- Refills that ship on your plan’s schedule
How KPV works
- Your gut lining has a transporter, PepT1, that’s scarce in healthy tissue and plentiful when it’s inflamed. It pulls KPV into the cells lining your gut and into immune cells, where KPV turns down NF-κB and MAP kinase, the signals that drive inflammation.
How to take it
- Prescribed as a topical or a form you swallow
- Your provider sets the dose and schedule
- Licensed U.S. providers
- State-licensed U.S. pharmacies
- Tracked shipping to your door
- Topical or oral
A licensed provider reviews every request.
A provider licensed in your state reads your health answers, decides whether KPV fits you and sets your dose. Questions later go straight to the Clinical chat in your portal.
Three steps to your door.
- Answer health questions
Online, in 3–5 minutes, on your own time.
- A provider reviews them
A licensed U.S. provider decides if KPV fits and sets your dose.
- It ships to you
A state-licensed U.S. pharmacy prepares it and ships it with tracking.
Studied since 1989, from colitis to skin cells.
Your gut lining has a transporter, PepT1, that’s scarce in healthy tissue and plentiful when it’s inflamed. It pulls KPV into the cells lining your gut and into immune cells, where KPV turns down NF-κB and MAP kinase, the signals that drive inflammation.
- Mice and human cells
KPV by mouth reduced colitis in mice. In human gut cells, tiny amounts calmed the main inflammation pathways.
Dalmasso et al. · Gastroenterology · 2008 - Mice
KPV sped recovery and reduced colon inflammation in two colitis models.
Kannengiesser et al. · Inflamm Bowel Dis · 2008 - Mice
Oral KPV in targeted nanoparticles reached the colon, sped healing of the gut lining and lowered TNF-α, a key inflammation signal.
Xiao et al. · Mol Ther · 2017 - Human skin cells
KPV protected human skin cells and a 3D skin model from inflammation and cell death caused by pollution particles.
Sung et al. · Tissue Cell · 2025 - Mice
KPV reduced chemically induced skin swelling, more at higher doses.
Hiltz et al. · FASEB J · 1989 - Rabbits
With KPV eye drops, every treated cornea had healed over by 60 hours. None on placebo had.
Bonfiglio et al. · Exp Eye Res · 2006
Questions before you start
Straight answers from the SuccessRx care team.
By mouth or on the skin?
By mouth for your gut, on your skin for skin. Your provider picks the form that fits what you’re treating.
Can I take KPV with BPC-157?
It’s a common pairing for the gut. Each is made as its own product, so your provider can prescribe both if they fit you.
Do I need a video visit?
Not in most states. Twelve states and Washington, D.C. require a short video visit by law, and the intake tells you if yours is one of them. Everywhere else, it’s online questions only.
How does it get to me?
Once your provider prescribes, a state-licensed U.S. pharmacy prepares your order and ships it with tracking. You can follow every step in your patient portal.
Can I cancel?
Yes. Pause, cancel or move your next refill date yourself in your patient portal, under Orders & Subscriptions. No phone call needed.
Who prescribes it?
A provider licensed in your state reviews your answers and decides whether KPV fits you. If it doesn’t, they’ll tell you why.
How do I reach someone?
Message the care team in your patient portal any time, or email hello@successrx.com. Medication questions go to the Clinical chat in your portal.
Find out if KPV fits you.
Ordering opens soon. Prices post on this page the day KPV is ready.
See what I can start todayOften compared with KPV
All treatments
Important safety information
Compounded medicines are prepared by a state-licensed pharmacy for one patient on a prescription. They are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality. Tell your provider about every medicine you take, and message the Clinical chat in your patient portal with any medication question.
Product images are illustrations; actual packaging may vary. Lifestyle photography is illustrative.