Semax
Nasal spray · coming soon
Semax is a 7-amino-acid peptide you take as a nasal spray. It has been a prescription medicine in Russia since the 1990s, used in stroke recovery and listed for preventing mental fatigue. Now it’s coming to SuccessRx: prescribed by a licensed provider and made by a state-licensed U.S. pharmacy.
Ordering opens soon
See what I can start todaySemax isn’t available to order yet. Prices post here the day it opens.
Prescribed by licensed U.S. providers. Prepared by state-licensed U.S. pharmacies.
What’s in your plan
- An online visit and review by a licensed U.S. provider
- Semax prepared for you by a state-licensed U.S. pharmacy
- Supplies and step-by-step instructions for your form
- Messaging with your care team in your patient portal
- Refills that ship on your plan’s schedule
How Semax works
- Semax is a short piece of ACTH, a hormone your body makes, with a 3-amino-acid tail that slows its breakdown. It has none of ACTH’s cortisol effects. In animal studies, it reaches the brain from the nose and raises BDNF, a protein that helps brain cells grow, connect and recover.
How to take it
- Prescribed as a nasal spray
- Your provider sets the dose and schedule
- Licensed U.S. providers
- State-licensed U.S. pharmacies
- Tracked shipping to your door
- Nasal spray
A licensed provider reviews every request.
A provider licensed in your state reads your health answers, decides whether Semax fits you and sets your dose. Questions later go straight to the Clinical chat in your portal.
Three steps to your door.
- Answer health questions
Online, in 3–5 minutes, on your own time.
- A provider reviews them
A licensed U.S. provider decides if Semax fits and sets your dose.
- It ships to you
A state-licensed U.S. pharmacy prepares it and ships it with tracking.
30 years of research, from neurology wards to brain scans.
Semax is a short piece of ACTH, a hormone your body makes, with a 3-amino-acid tail that slows its breakdown. It has none of ACTH’s cortisol effects. In animal studies, it reaches the brain from the nose and raises BDNF, a protein that helps brain cells grow, connect and recover.
- Humans · 110 people
After a stroke, two 10-day courses of Semax raised blood BDNF and sped recovery of daily function.
Gusev et al. · Zh Nevrol Psikhiatr · 2018 - Humans · 110 people
Given early after a stroke, Semax sped recovery of neurological function, mainly movement, versus standard therapy alone.
Gusev et al. · Zh Nevrol Psikhiatr · 1997 - Healthy humans · 24 people
One dose changed the brain’s resting-state network on fMRI compared with placebo.
Lebedeva et al. · Bull Exp Biol Med · 2018 - Healthy humans
Single nasal doses produced brain-wave changes like other cognitive enhancers and improved operators’ work performance.
Kaplan et al. · Neurosci Res Commun · 1996 - Rats
One dose in the nose raised BDNF in the hippocampus, the brain’s memory center, about 1.4-fold and improved learning.
Dolotov et al. · Brain Res · 2006 - Rats
Semax reversed stress-induced loss of pleasure (anhedonia) and restored BDNF in the hippocampus.
Inozemtseva et al. · Eur J Pharmacol · 2024
Questions before you start
Straight answers from the SuccessRx care team.
How do I take Semax?
As a nasal spray. No needles. Your provider sets how much and how often.
Is Semax approved anywhere?
Yes, in Russia. It’s a prescription medicine there, made as nasal drops, and it’s on the country’s list of essential drugs.
Do I need a video visit?
Not in most states. Twelve states and Washington, D.C. require a short video visit by law, and the intake tells you if yours is one of them. Everywhere else, it’s online questions only.
How does it get to me?
Once your provider prescribes, a state-licensed U.S. pharmacy prepares your order and ships it with tracking. You can follow every step in your patient portal.
Can I cancel?
Yes. Pause, cancel or move your next refill date yourself in your patient portal, under Orders & Subscriptions. No phone call needed.
Who prescribes it?
A provider licensed in your state reviews your answers and decides whether Semax fits you. If it doesn’t, they’ll tell you why.
How do I reach someone?
Message the care team in your patient portal any time, or email hello@successrx.com. Medication questions go to the Clinical chat in your portal.
Find out if Semax fits you.
Ordering opens soon. Prices post on this page the day Semax is ready.
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Important safety information
Compounded medicines are prepared by a state-licensed pharmacy for one patient on a prescription. They are not FDA-approved, and the FDA does not review them for safety, effectiveness or quality. Tell your provider about every medicine you take, and message the Clinical chat in your patient portal with any medication question.
Product images are illustrations; actual packaging may vary. Lifestyle photography is illustrative.